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Vitamin B12 shots are direct injections of the essential B12 vitamin, crucial for energy, brain health, and red blood cell production

This means that if a significant amount of B12 in your blood is 'inactive', the fact that you are deficient will NOT show that you are indeed deficient

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B12 has other benefits, too, including improved sleep, concentration, cellular function, and immunity

A 2021 review of NNMT as a metabolic target stated plainly that clinical trials targeting NNMT have not been reported until now (Liu 2021, PMID 34368359) [5], and that held into 2026